Axon Ligands (TM) - alphabetic: [A] [B] [C] [D] [E] [F] [G] [H] [I] [J] [K] [L] [M] [N] [O] [P] [Q] [R] [S] [T] [U] [V] [W] [X] [Y] [Z]

NSC 348884

CAS 81624-55-7

C38H40N10  MW 636.81

Purity: 99%

Soluble in DMSO to 18 mM

Ordering Information:

Cat. No. Axon 1402    Prime Source 

Qty1: 10 mg / €125  $163

Promotion: 2 x 10 mg  @  €200  $260

Qty1: 50 mg / €425  $553

Promotion: 2 x 50 mg  @  €680  $884

Qty3: on request (*in stock of grams)

Send enquiry to: order@axonmedchem.com

or by fax to: +31-50-3600390.

Contact us for payment and tech support.

Biological Activity:   A putative small molecule inhibitor of nucleophosmin (NPM). NSC 348884 inhibits NMP oligomer formation, up-regulates p53, induces apoptosis and synergizes with chemotherapy.   References: online 1   W Qi et al. NSC348884, a nucleophosmin inhibitor disrupts oligomer formation and induces apoptosis in human cancer cells. Oncogene  2008, 27(30), 4210-4220.  [online]       Chemical Name: N,N,N',N'-Tetrakis-(5-methyl-1H-benzoimidazol-2-ylmethyl)-ethane-1,2-diamine

NSC 348884 | Nucleophosmin (NPM) inhibitor | Axon Medchem | Axon 1402 | NSC348884

Axon Ligands ^TM  - Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.

axonmedchem.com © 2012