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AZD 7762 hydrochloride

CAS 860352-01-8 (free base)

C17H19FN4O2S.HCl  MW 398.89

Purity: 99% (optically pure)

Soluble in DMSO

Ordering Information:

Cat. No. Axon 1399   Prime Source

Qty1: 2 mg (research sample) / €95  $124

Qty2: 5 mg (research sample) / €145  $189 

Promotion: 2 x 5 mg @ €220  $286    

Qty3: 25 mg (research sample) / €475  $618

Promotion: 2 x 25 mg @ €720  $936    

Qty4: on request

Send enquiry to: order@axonmedchem.com

or by fax to: +31-50-3600390.

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Biological Activity:   Checkpoint kinase (CHK) inhibitor.   References: online 1, 2, 3   JW Janetka et al, Inhibitors of Checkpoint Kinases: From discovery to the clinic. Curr. Opin. Drug Discov. & Devel. 2007, 10(4), 473-486.   S. Ashwell and S Zabludoff. DNA Damage Detection and Repair Pathways Recent Advances with Inhibitors of Checkpoint Kinases in Cancer Therapy. Clin. Cancer Res. 2008, 14(13), 4033-4037.   SD Zabludoff et al. AZD7762, a novel checkpoint kinase inhibitor, drives checkpoint abrogation and potentiates DNA-targeted therapies. Mol. Cancer Ther. 2008, 7(9), 2955-2966.   L Carrassa et al. Role of Chk1 in the differentiation program of hematopoietic stem cells. Cell. Mol. Life Sci. 2010, 67, 1713–1722. [online]     Chemical Name: 5-(3-Fluoro-phenyl)-3-ureido-thiophene-2-carboxylic acid (S)-piperidin-3-ylamide hydrochloride

AZD 7762 | CHK inhibitor | Axon Medchem | Axon 1399 | AZD7762

Axon Ligands ^TM - Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.

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Prime Source Informotion

AZD7762 from Axon Medchem is fully QC confirmed and bioactivity proved ligand as drug standard.

Be careful that de-fluoration may happen in certain circumstances in its chemistry and make sure that you have not procured de-Fluoro analogue of AZD7762 from other source(s).