Axon Ligands (TM) - alphabetic: [A] [B] [C] [D] [E] [F] [G] [H] [I] [J] [K] [L] [M] [N] [O] [P] [Q] [R] [S] [T] [U] [V] [W] [X] [Y] [Z]

Sunitinib malate

SU-11248 - Sutent

CAS 341031-54-7

C22H27FN4O2.C4H6O5 MW 532.56

Purity: 99%

Ordering Information:

Cat. No. Axon 1398  

Qty1: 10 mg (research sample) / €85  $111 

Promotion: 2 x 10 mg  /  €120   $156 

Qty2: 50 mg  (research sample) / €255  $332 

Promotion: 2 x 50 mg  /  €350   $455 

Qty3: on request contract research synthesis

Send enquiry to: order@axonmedchem.com

or by fax to: +31-50-3600390.

Contact us for our product range and services.

Biological Activity:   Small molecule multi-targeted receptor tyrosine kinase (RTK) inhibitor. Sunitinib inhibits cellular signaling by targeting multiple RTKs, including PDGF-R/VEGF-R.     References: online 1   RJ Motzer et al. Sunitinib versus interferon alfa in metastatic renal-cell carcinoma. N Engl J Med 2007, 356(2), 115–124. doi:10.1056/NEJMoa065044. PMID 17215529.    ED Deeks and GM Keating. Sunitinib.  Drugs 2006, 66, 2255-2266.   TJ Abrams, et al. SU11248 Inhibits KIT and Platelet-derived Growth Factor Receptor β in Preclinical Models of Human Small Cell Lung Cancer.  Mol. Cancer Ther. 2003, 2, 471-478.     Chemical Name: N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidine)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide malate

Sunitinib | RTK inhibitor | Axon Medchem | Axon 1398 | SU 11248 - Sutent

Axon Ligands ^TM - Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.

axonmedchem.com © 2011

Axon Ligands In The Field: