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Gefitinib

ZD 1839 - Iressa

 

CAS 184475-35-2

C22H24ClFN4O3  MW 446.90

Purity: 99%

 

 

 

 

Ordering Information:

 

Cat. No. Axon 1393      Prime Source

 

Qty1: 10 mg (research sample) / €85  $111

Promotion: 2 x 10 mg @ €120  $156

Qty2: 50 mg (research sample) / €255  $332

Promotion: 2 x 50 mg @ €380  $494

Qty3: on request

 

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Biological Activity:

 

Selective epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor.

 

References: online 1

 

G Blackledge, S Averbuch. Gefitinib ('Iressa', ZD1839) and new epidermal growth factor receptor inhibitors. Br. J. Cancer 2004, 90(3), 566-72 (review).

 

JG Paez et al. EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy. Science 2004, 304(5676), 1497-500.

 

 

Chemical Name: N-(3-chloro-4-fluoro-phenyl)-7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-amine

 

Gefitinib | EGFR inhibitor | Axon Medchem | Axon 1393 | ZD 1839 - Iressa - ZD1839

Axon Ligands TM - Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.

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Axon Ligands In The Fields:

 

BIBW 2992 | EGFR/HER2 inhibitor

CI 1033 | EGFR inhibitor

CP 724714 | HER2 inhibitor

EGFR inhibitor [879127-07-8]

Erlotinib | EGFR inhibitor

Gefitinib | EGFR inhibitor

Lapatinib | EGFR/HER2 inhibitor

Neratinib | EGFR/HER2 inhibitor

OSI 420 | EGFR inhibitor

Pelitinib | EGFR inhibitor

Vandetanib | VEGFR/EGFR inhibitor

WZ4002 | EGFR T790M inhibitor

 

 

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