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Varenicline dihydrochloride

Chantix - Champix (as tartrate)

CAS 249296-44-4

 C13H13N3 MW 211.267+2HCl

Purity: 99%

Ordering Information:

Cat. No. Axon 1384      

Qty1: 5 mg (research sample) / €105  $137

Qty2: 25 mg (research sample) / €315  $410

Qty3: on request contract research synthesis

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Biological Activity:   Selective α4β2 nicotinic acetylcholine receptor partial agonist; Smoking cessation drug.   References: online 1, 2, 3, 4   DE Jorenby et al. Efficacy of varenicline, an alpha4beta2 nicotinic acetylcholine receptor partial agonist, vs placebo or sustained-release bupropion for smoking cessation: a randomized controlled trial". JAMA 2006,296 (1), 56–63.   RS Obach et al. Metabolism and disposition of varenicline, a selective alpha4beta2 acetylcholine receptor partial agonist, in vivo and in vitro. Drug Metab Dispos 2006, 34, 121-30.   Chemical Name:7,8,9,10-tetrahydro-6,10-methano-6H-pyrazino(2,3-h)(3)benzazepine dihydrochloride

Varenicline | Nicotinic partial agonist | Axon Medchem | Axon 1384 | Chantix - Champix

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Axon Ligands ^TM

Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.