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Amisulpride

DAN 2163

CAS 71675-85-9

C17H27N3O4S  MW 369.78

Purity: >98%

Ordering Information:

Cat. No. Axon 1381

Qty1: 10 mg / €45  $59

Qty2: 50 mg / €85  $111

Qty3: on request

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Biological Activity:   Dopamine D2 and D3 receptor antagonist (Ki 2.8 and 3.2 nM for D2 and D3 respectively); Claimed to be atypical antipsychotic with low incidence of EPS.   References: online 1, 2   H Loo et al. Amisulpride versus placebo in the medium-term treatment of the negative symptoms of schizophrenia. Br. J. Psychiatry 1999, 170, 18-22.   H Choemaker et al. Neurochemical characteristics of amisulpride, an atypical dopamine D2/D3 receptor antagonist with both presynaptic and limbic selectivity. J. Pharmacol. Exp. Ther. 1997, 280/1, 83-97.         Chemical Name:4-amino-N-[(1-ethylpyrrolidin-2-yl)methyl]-5-ethylsulfonyl-2-methoxy-benzamide

Amisulpride | D2 and D3 antagonist | Axon Medchem | Axon 1381 | DAN 2163

Axon LigandsTM - Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.

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