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PI 103 hydrochloride

CAS 371935-74-9

371935-91-0 (HCl)

C19H16N4O3.HCl  MW 384.82 

Purity: 99%

Ordering Information:

Cat. No. Axon 1380            

Qty1: 2 mg /  €60  $78

Qty2: 5 mg /  €95  $124

Qty3: 25 mg / €350  $455

Qty4: on request

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Biological Activity:   A selective class I PI3K inhibitor; it inhibits PI3K p110 isoforms, mTOC1 and also DNA-PK; a valuable tool compound.   References: online 1, 2, 3   ZA Knight et al. A Pharmacological Map of the PI3-K Family Defines a Role for p110α in Insulin Signaling. Cell 2006, 125, 733–747.   FI Raynaud, et al. Pharmacologic characterization of a potent inhibitor of class I phosphatidylinositide 3-kinases. Cancer Res. 2007, 67(12), 5840-50. [article]       Chemical Name: 3-[4-(4-Morpholinylpyrido[3',2':4,5]furo[3,2-d]pyrimidi n-2-yl]phenol hydrochloride

PI 103 | PI3K inhibitor | Axon Medchem | Axon 1380 | PI103

Axon Ligands ^TM - Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.

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