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MK 677 - Ibutamoren mesylate

L-163194

CAS 159634-47-6 (parent),

159752-10-0 (salt)

  C28H40N4O8S2 MW 624.77

Purity: 99% (optically pure)

Soluble in water to 100 mM

Ordering Information:

Cat. No. Axon 1376    Prime Source

Qty1: 5 mg (research sample) / €135  $176

Promotion: 10 mg @ €180  $234

Qty2: 25 mg (research sample) / €475  $618

Promotion: 50 mg @ €680  $884

Qty3: on request

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Biological Activity:   Potent and orally active growth hormone (GH) secretagogue.   References: online 1, 2, 3, 4, 5   T Jacks et al. MK-0677, a potent, novel, orally active growth hormone (GH) secretagogue: GH, insulin-like growth factor I, and other hormonal responses in beagles. Endocrinology, 1996, 137, 5284-5289.   MG Murphy et al. MK-677, an Orally Active Growth Hormone Secretagogue, Reverses Diet-Induced Catabolism. J. Clin. Endocrinol. Meta. 1998, 83, (2), 320-325.   LA Sorbera et al. Ibutamoren Mesylate. Drugs Fut. 2006, 31(5), 390.   E Codner et al. Effects of oral administration of ibutamoren mesylate, a nonpeptide growth hormone secretagogue, on the growth hormone–insulin-like growth factor I axis in growth hormone–deficient children. Clin. Pharmacol. Ther. 2001, 70, 91–98.     Chemical Name: 2-amino-2-methyl-N-[(2R)-1-(1-methylsulfonylspiro[2H-indole-3,4'-piperidine]-1'-yl)-1-oxo-3-(phenylmethoxy)propan-2-yl]propanamide methanesulfonic acid

MK 677 - Ibutamoren | GH secratagogue | Axon Medchem | Axon 1376 | MK0677 - MK677 - MK-0677

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Axon Ligands ^TM    

Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.