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Atipamezole hydrochloride Antisedan - MPV 1248

CAS 104054-27-5 (parent)

104075-48-1 (HCl)

  C14H16N2.HCl  MW 248.76

Purity: 99%

Soluble in water and DMSO

Ordering Information:

Cat. No. Axon 1371    

Qty1: 5 mg / €95  $124

Qty2: 25 mg / €285  $371 

Qty3: on request

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Biological Activity:   A competitive α2-adrenergic antagonist; used to antagonize (reverse) the action of the α2 adrenoceptor agonists medetomidine, xylazine and detomidine.   References: online 1, 2   R Virtanen et al. Highly selective and specific antagonism of central and peripheral alpha 2-adrenoceptors by atipamezole. Arch. Int. Pharmacodyn. Ther. 1989, 297 190-204. [online] K Puurunen et al. An α2-adrenergic antagonist, atipamezole, facilitates behavioral recovery after focal cerebral ischemia in rats. Neuropharmacol. 2001, 40, 597-606. [online]   CW Jurgens et al. Alpha2A adrenergic receptor activation inhibits epileptiform activity in the rat hippocampal CA3 region. Mol Pharmacol. 2007, 71(6), 1572-1581. [online]     Chemical Name: 5-(2-Ethyl-indan-2-yl)-1H-imidazole hydrochloride

Atipamezole | α2 antagonist | Axon Medchem | Axon 1371 | Antisedan - MPV 1248

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Axon Ligands in the area:

Atipamezole | α2 antagonist

B-HT 920 | α2 and D2 agonist

B-HT 933 | α2 agonist

B-HT 958 | α2 partial & D2 agonist

Efaroxan | α2 antagonist

ST-91 | α2 agonist