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STA 5326  -  Apilimod

CAS 541550-19-0

C23H26N6O2 MW 418.50

Purity: 99%

Ordering Information:

Cat. No. Axon 1369       Exclusive Promotion

Qty1: 5 mg (research sample) / €115  $150

Promotion: 2 x 5 mg @ €172  $224

Qty2: 25 mg (research sample) / €415  $540   

Promotion: 2 x 25 mg @ €622  $809

Qty3: on request contract research synthesis

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Biological Activity:   Potent and orally active inhibitor of the cytokines interleukin-12 (IL-12), and interleukin-23 (IL-23) production; potential regulators of certain autoimmune and inflammatory diseases.   References:   Wada et al: Selective abrogation of Th1 response by STA-5326, a potent IL-12/IL-23 inhibitor. Blood, 2007, 109(3), 1156-1164.   Wada et al: IL-12/IL-23 inhibitors: a promising approach to the treatment of inflammatory disorders. Drugs Fut. 2008, 33(1), 49-63.     Chemical Name: 4'-Acetyl-biphenyl-4-carboxylic acid {4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-amide

STA 5326 | IL-12 and IL-23 production inhibitor | Axon Medchem | Axon 1369 | STA5326 - STA-5326 - Apilimod

Axon Ligands ^TM  - Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.

Axon Ligands In The Field:

STA 5326 | IL-12/23 inhibitor

PD 0220245 | IL-8 antagonist

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