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LY 294002

CAS 15447-36-6

C19H17NO3  MW 307.35

Purity: 99%

Soluble in DMSO

Ordering Information:

Cat. No. Axon 1366

Qty1: 5 mg / €85  $111

Promotion: 2 x 5 mg / €120  $156

Qty2: 25 mg / €255  $332

Promotion: 2 x 25 mg / €380  $494

Qty3: on request

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Biological Activity:   Specific PI3K inhibitor with IC50 value of 1.4 micromolar; LY294002 is a reversible inhibitor of PI3K whereas wortmannin acts irreversibly.   References: online   MH Cardone et al. Regulation of Cell Death Protease Caspase-9 by Phosphorylation. Science 1998, 282, 1318.   CJ Vlahos et al. A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002). J. Biol. Chem. 1994, 269, 5241-5248.       Chemical Name: 2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one

LY 294002 | PI3K Inhibitor | Axon Medchem | Axon 1366 | LY294002

Axon Ligands^TM - Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.

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