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WAY 100135 dihydrochloride

.2HCl

CAS 149055-79-8 (2HCl)

133025-23-7 (parent)

C24H33N3O2.2HCl  MW 468.47

Purity: 99%

Ordering Information:

Cat. No. Axon 1360  

Qty1: 10 mg / €75  $98

Qty2: 50 mg / €275  $358

Qty3: on request

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Biological Activity:   Highly selective 5-HT1A antagonist.   * Its two enantiomers, (S)-WAY100135 (Axon 1341) and (R)-WAY100135 (Axon 1359), are also available.   References: online 1, 2, 3   K Wdzony et al. WAY 100135, an Antagonist of 5-HT1A Serotonin Receptors, Attenuates Psychotomimetic Effects of MK-801. Neuropsychopharmacology 2000, 23, 547-559.   KF Rhodes et al. The antagonist actions of WAY 100135 and its enantiomers on 5-HT1A receptor-mediated hyperpolarization of the rat isolated superior cervical ganglion. Naunyn-Schmiedeberg's Arch. Pharmacol. 1993, 348(3), 225-227.   NA Escandon, DC Zimmermann and RB McCall. Characterization of the serotonin1A receptor antagonist activity of WAY- 100135 and spiperone. J Pharmacol. Exp. Ther. 1994, 268, 441-447.     Chemical Name: N-tert-Butyl-3-[4-(2-methoxy-phenyl)-piperazin-1-yl]-2-phenyl-propionamide dihydrochloride

WAY 100135 | 5-HT1A antagonist | Axon Medchem | Axon 1360 | WAY100135

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