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Quetiapine fumarate

ICI 204636 - ZD 5077 - ZM 204636 - FK 949 

CAS 111974-69-7, 111974-72-2 (salt)

C21H25N3O2S.1/2C4H4O4 

MW 441.55  Purity: 99%  

Ordering Information:

Cat. No. Axon 1354

Qty1: 10 mg (research sample) / €75  $98

Qty2: 50 mg (research sample) / €175  $228

Qty3: on request

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Biological Activity:   Atypical antipsychotic; Quetiapine is a moderate 5-HT2, weak dopamine D2 and α2 receptor antagonist.   References: online   PT Thyrum et al: Multi-dose pharmacokinetics of ICI 204, 636 in elderly patients with selected psychotic disorders. Psychopharmacol. Bull 1996, 32(3), 524.   C Vesely et al. Remission of severe tardive dyskinesia in a shizophrenic patient treated with atypical antipsychotic substance quetiapine. Int. Clin. Psychopharmacol. 2000, 15, 57-60.     Chemical Name:2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]-ethanol-(E)-2-butanedioate (2:1) salt

Quetiapine | Atypical antipsychotic | Axon Medchem | Axon 1354 | Seroquel

Axon LigandsTM - Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.

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Axon Atypical Antipsychotics available: e.g.

Amisulpride (Axon 1381)

Aripiprazole (Axon 1143)

Clozapine (Axon 1146)

GMC 1-169 (Axon 1148)

GMC 2-83 (Axon 1150)

GMC 61-39 (Axon 1149)

Olanzapine (Axon 1298)

Quetiapine (Axon 1354)

Sertindole (Axon 1141)

Thio-aripiprazole (Axon 1144)

Ziprasidone (Axon 1446)

"Typical Antipsychotic":

Isoclozapine (Axon 1147)

Clozapine Analogues:

GMC 1-116 (Axon 1151)

GMC 1-165(Axon 1152)