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Axon Ligands (TM) - alphabetic: [A] [B] [C] [D] [E] [F] [G] [H] [I] [J] [K] [L] [M] [N] [O] [P] [Q] [R] [S] [T] [U] [V] [W] [X] [Y] [Z]

 

 

 

  

Lamotrigine

 

 

CAS 84057-84-1

C9H7Cl2N5 

MW 256.1

 

 

 

 

Ordering Information:

 

Cat. No. Axon 1353

 

Qty1: 10 mg / €75  $98

 

Qty2: 50 mg / €250  $325

 

Qty3: on request

 

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or by fax to: +31-50-3600390.

 

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Biological Activity:

 

Glutamate antagonist and sodium channel blocker; an anticonvulsant drug. 

 

References: online 1

 

L Barbosa et al. A double-blind, randomized, placebo-controlled trial of augmentation with lamotrigine or placebo in patients concomitantly treated with fluoxetine for resistant major depressive episodes. J. Clin. Psychiatry. 2003, 6(4), 403–407.

 

WJ Curry and DL Kulling. Newer Antiepileptic Drugs: Gabapentin, Lamotrigine, Felbamate, Topiramate and Fosphenytoin. Am. Fam. Physician. 1998, 57(3), 513.

 

 

 

 

 

Chemical Name: 6-(2,3-Dichloro-phenyl)-[1,2,4]triazine-3,5-diamine

 

Lamotrigine | Glutamate antagonist | Axon Medchem | Axon 1353

axonmedchem.com © 2012

 

Axon Ligands in EAA field:

 

CP 101606 | NMDA antagonist

Ifenprodil | NMDA antagonist

Eliprodil | NMDA antagonist

N20C | NMDA antagonist

Gavestinel | Glycine antagonist

Ro 25-6981 | NMDA antagonist

Lamotrigine | Glutamate antago.

 

CFM-2 | AMPA antagonist

CNQX | AMPA/kanaite antagonist

DNQX | AMPA/kainate antagonist

GYKI 53655 | AMPA antagonist

YM-90K | AMPA antagonist

 

AZ 12216052 | mGluR8 PAM

BINA | mGluR2 PAM

CPPHA | mGluR5 PAM

(S)-3,5-DHPG | mGluR1 agonist

VU-29 | mGuR5 PAM

LY 367385 | mGluR1a antagonist

YM 298198 | mGluR1 antagonist

Fenobam | mGluR5 antagonist

MPEP | mGluR5 antagonist