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Biological Activity:
Melatonin antagonist; MT2 selective
References: online 1, 2
MT Teh & D Sugden. Comparison of the structure-activity relationships of melatonin receptor agonists and antagonists: lengthening the N-acyl side-chain has differing effects on potency on Xenopus melanophores. Naunyn Schmiedebergs Arch. Pharmacol. 1998, 358, 522.
KN Ting et al. Molecular and pharmacological evidence for MT1 melatonin receptor subtype in the tail artery of juvenile Wistar rats. Br. J. Pharmacol. 1999, 127, 987.
Chemical Name: Pentanoic acid [2-(2-benzyl-1H-indol-3-yl)-ethyl]-amide; or N-Pentanoyl-2-benzyltryptamine
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