Axon Ligands (TM) - alphabetic: [A] [B] [C] [D] [E] [F] [G] [H] [I] [J] [K] [L] [M] [N] [O] [P] [Q] [R] [S] [T] [U] [V] [W] [X] [Y] [Z]

Luzindole

N-0774 

CAS 117946-91-5

C19H20N2O  MW 292.38

Purity: 99%

Ordering Information:

Cat. No. Axon 1350

Qty1: 10 mg / €95  $124

Qty2: 50 mg / €335  $436

Qty3: on request

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Biological Activity:   A putative melatonin antagonist   References: online 1, 2   C Browning et al., Pharmacological characterization of human recombinant melatonin MT(1) and MT(2) receptors. Br. J. Pharmacol. 2000,129, 877-886.   ML Dubocovich. Luzindole (N-0774): a novel melatonin receptor antagonist. J. Pharmacol. Exp. Ther. 1988, 246 902-910.   M Zhou et al. Luzindole, a melatonin receptor antagonist, inhibits the transient outward K+ current in rat cerebellar granule cells. Brain Res. 2003, 970, 169-171.     Chemical Name: N-[2-(2-Benzyl-1H-indol-3-yl)-ethyl]-acetamide

Luzindole | Melatonin antagonist | Axon Medchem | Axon 1350

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Axon Ligands In The Field:

AH 001 | Melatonin agonist

AH 002 | Melatonin agonist

DH 97 | Melatonin MT2 antagonist

Luzindole | Melatonin antagonist 

Axon Ligands ^TM

Research chemicals for biological study. Some high-profile ligands could be provided under terms of contract research synthesis.