PIK 75 hydrochloride

Based on 20 reference(s) in Google Scholar 80 100 20

Axon 1334

CAS [1462995-14-7]

MF C16H14BrN5O4S.HCl
MW 488.74

Purity: 99%
Moderately soluble in DMSO

PIK 75 hydrochloride

Description

PI3K p110α specific inhibitor; IC50 values (nM): 7.8 (p110α), 343 (p110β), 907 (p110δ) (Chaussade et al reported).

ZA Knight et al. A Pharmacological Map of the PI3-K Family Defines a Role for p110α in Insulin Signaling. Cell 2006, 125, 733–747.

C Chaussade et al. Evidence for functional redundancy of class IA PI3K isoforms in insulin signalling. Biochem J. 2007, 404(3), 449–458.

S Kim et al. Insulin-like growth factor-1 regulates platelet activation through PI3-Kα isoform. Blood, 2007, 110(13), 4206-4213.

List of publications using PIK 75 (Axon 1334) purchased from Axon Medchem

PI3K inhibitor (p110-α specific)

Chemical name

N'-[(1E)-(6-bromoimidazo[1,2-a]pyridin-3-yl)methylene]-N,2-dimethyl-5-nitrobenzenesulfonohydrazide hydrochloride

Parent CAS No.

[945619-31-8]

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Size	Unit Price	Stock
5 mg	€70.00	In Stock
25 mg	€200.00	In Stock

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Size	Unit Price	Stock
2 x 5 mg	€100.00	In Stock
2 x 25 mg	€300.00	In Stock

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