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DMP 543

CAS 160588-45-4

C26H18F2N2O MW 412.44

Purity: 99%

Ordering Information:

Cat. No. Axon 1322         

Qty1: 10 mg / €95  $124   

Promotion: 2 x 10 mg @ €140  $182

Qty2: 50 mg / €335  $435 

Promotion: 2 x 50 mg @ €480  $624

Qty3: on request

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Biological Activity:   neurotransmitter release enhancer, K+ channel blocker and acetylcholine release stimulator; potential AD therapeutic.   References: online ref 1, 2, 3 Zaczek et al. Two new potent neurotransmitter release enhancers, 10,10-Bis(4-pyridinylmethyl)-9(10H)-anthracenone and 10,10-Bis(2-flouro-4-pyridinylmethyl) -9(10H)-anthracenone: comparison to linopirdine. J. Pharmacol. Exp. Ther. 1998, 285, 724. Chorvat et al. Ion channel modulator that enhance acetylcholine release: potential therapies for Alzheimer's disease. Exp. Opin. Invest. Drugs. 1998, 7(4), 499-518. Camps et al. Cholinergic Drugs in Pharmacotherapy of Alzheimer's Disease. Mini Rev. Med. Chem, 2002, 2, 11-25.

DMP 543 | K channel blocker and ACh release enhancer | Axon Medchem | Axon 1322 - DMP543

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