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Antalarmin hydrochloride

.HCl

CAS220953-69-5

C₂₄H₃₄N₄·HCl  MW 415.01

Purity: 99%

Ordering Information:

Cat. No.: Axon 1321 

Qty1: 10 mg / €105  $137        

Qty2: 50 mg / €365  $475

Qty3: on request

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Biological Activity:   Non-peptide CRF1 corticotropin-releasing factor receptor antagonist.   References: onlineref 1, 2   EL Webster et al. In vivo and in vitro characterization of antalarmin, a nonpeptide corticotropin-releasing hormone (CRH) receptor antagonist: suppression of pituitary ACTH release and peripheral inflammation. Endocrinology, 1996, 137, 5747-5750.   EM Jutkiewicz et al. The effects of CRF antagonists, antalarmin, CP154,526, LWH234, and R121919, in the forced swim test and on swim-induced increases in adrenocorticotropin in rats. Psychopharmacology (Berl). 2005, 180(2), 215-223.   Chemical name: N-Butyl-N-ethyl-2,5,6-trimethyl-7-(2,4,6-trimethylphenyl)-7H-pyrrolol[2,3-d]pyrimidin-4-amine hydrochloride

Antalarmin | CRF-1 Antagonist | Axon Medchem | Axon 1321

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Axon Ligands in the field:

Antalarmin | CRF-1 Antagonist

CP 154526 | CRF-1 Antagonist

Axon Ligands ^TM    

Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.