Ro 25-6981 | NMDA antagonist | Axon Ligands | Axon Medchem

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Ro 25-6981 hydrochloride

CAS169274-78-6 (free base)

C22H29NO2ˇHCl MW 375.93

Purity: >99% ee de

Water soluble to 66 mM

Ordering Information:

Cat. No. Axon 1314 Prime Source

Qty1: 10 mg / 110 $143

Qty2: 50 mg / 410 $533

Qty3: on request (in stock of multigrams)

Send enquiry to: order@axonmedchem.com

or by fax to: +31-50-3600390.

Biological Activity:

Potent and selective antagonist of NMDA glutamate receptors containing the NR2B subunit; Optimal salt form, which is more water soluble than its maleate.

References: online (ref 1)

Fischer et al. Ro 25-6981, a highly potent and selective blocker of N-Methyl-D-aspartate receptors containing the NR2B subunit. Characterization in vitro. J. Pharmacol. Exp. Ther. 1997, 283, 1285.

Chemical Name:(aR,bS)-a-(4-Hydroxyphenyl)-b-methyl-4-(phenylmethyl)-1 -piperidinepropanol hydrochloride

Ro 25-6981 | NMDA antagonist | Axon Medchem | Ro25-6981 | Ro 256981 | Ro256981 supplier

Axon Ligands ^TM - Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.