1-EBIO | KCa Channel Opener | Axon Ligands | Axon Medchem

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1-EBIO

CAS 10045-45-1

C9H10N2O MW 162.19

Purity: 99%

Soluble in DMSO and EtOH

Ordering Information:

Cat. No. Axon 1313

Qty1: 10 mg / €55 $72

Promotion: 25 mg @ €100 $130

Qty2: 50 mg / €165 $215

Promotion: 100 mg @ €250 $325

Qty3: on request (* in stock of grams)

Send enquiry to: order@axonmedchem.com

or by fax to: +31-50-3600390.

Biological Activity:

Ca²⁺-activated K⁺-channel opener; induces hyperpolarization to the same magnitude as ACh in aortic value endothelial cells.

References:

AS Adeagbo. 1-Ethyl-2-benzimidazolinone stimulates endothelial KCa channels and nitric oxide formation in rat mesenteric vessels. Eur. J. Pharmacol. 1999, 379, 151-159. [online]

K.L. Hamilton, L. Meads and A.G. Butt. 1-EBIO stimulates Cl- secretion by activating a basolateral K+ channel in the mouse jejunum. Eur. J. Physiol. 1999,
439(1-2), 158-166. [online]

N Kusama et al. Reduced hyperpolarisation in endothelial cells of rabbit aortic value following chronic nitroglycerine administration. Br. J. Pharmacol. 2005, 146, 487. [online]

Chemical Name: 1-Ethyl-2-benzimidazolinone

1-EBIO | KCa channel openor | Axon Medchem | Axon 1313

Axon Ligands ^TM - Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.