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Biological Activity:
A microtuble-binding molecule and reversible inhibitor of tubulin polymerization; potential angiogenesis inhibitor
References: online 1 2
GR Rosania et al. Myoseverin, a novel microtubule-binding molecule with novel cellular effects. Nat. Biotechnol. 2000, 18, 307-308.
OD Perez et al. Inhibition and reversal of myogenic differentiation by purine-based microtuble assembly inhibitors. Chem. Biol. 2002, 9, 475-483.
HE Park et al. Myoseverin Is a Potential Angiogenesis Inhibitor by Inhibiting Endothelial Cell Function and Endothelial Progenitor Cell Differentiation.
DNA and Cell Biol. 2006, 25(9), 514-522. [online]
Chemical Name:9-Isoproyl-N2,N6-bis-(4-methoxybenzyl)-9H-purine-2,6-diamine
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