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(+/-)-BMS-204352

CAS 183720-28-7

C16H10ClF4NO2  MW 359.71

Purity: 98%

Ordering Information:

Cat. No. Axon 1308

Qty1: 5 mg (research sample) / inquire

Qty2: 25 mg (research sample) / inquire

Qty3: on request contract research synthesis

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Biological Activity:   Potassium channel opener; racemate of more active S-(+)-enantiomer, BMS-204352 (Flindokalner, Axon 1112), and less active R-(-)-enantiomer (Axon 1309).   References: online ref 1, 2   Krishna R et al. Pharmacokinetics and dose proportionality of BMS-204352 after intraarterial administration to rats. Biopharm Drug Dispos. 2002, 23(6), 233-7.   M. P. G. Korsgaard et al. Anxiolytic Effects of Maxipost (BMS-204352) and Retigabine via Activation of Neuronal Kv7 Channels. J. Pharmacol. Exp. Ther. 2005, 314, 282-292.     Chemical Name: (+/-)-(5-Chloro-2-methoxyphenyl)-3-fluro-6-(trifluoromethyl)-2,3-dihydro-1H-indol-2-one

(±)-BMS 204352 | K channel opener | Axon Medchem | Axon 1308 | (+/-)-BMS204352

Axon Ion Channel Modulators: