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Axon Ligands (TM) - alphabetic: [A] [B] [C] [D] [E] [F] [G] [H] [I] [J] [K] [L] [M] [N] [O] [P] [Q] [R] [S] [T] [U] [V] [W] [X] [Y] [Z]

 

 

 

  

JNJ 7777120

 

 

CAS 459168-41-3

C18H20ClN3O5  MW 393.83

Purity: >99%

 

 

 

 

 

Ordering Information:

 

Cat. No. Axon 1306

 

1 x 10 mg / 85  $111

1 x 50 mg / 295  $384

Bulk on request

 

Send enquiry to: order@axonmedchem.com

or USorders@axonmedchem.com

 

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Biological Activity:

 

First potent and selective non-imidazole H4 antagonist

 

 

References: online ref 1, 2

 

C Varga et al. Inhibitory effects of histamine H4 receptor antagonists on experimental colitis in the rat. Eur. J. Pharmacol. 2005, 522(1-3), 130-138.

 

 

 

 

Chemical Name: (5-Chloro-1H-indol-2-yl)-(4-methyl-piperazin-1-yl)-methanone

 

JNJ 7777120 | H4 antagonist | Axon 1306 | JNJ7777120 from supplier Axon Medchem

 

axonmedchem.com 2013

 

Axon Histamine Receptor (HR) Ligands available: e.g.

 

A 943931 | H4 antagonist

JNJ 7777120 | H4 antagonist

JNJ 10191584 | H4 antagonist

4-Methylhistamine | H4 agonist

VUF 10460 | H4 agonist

 

Fexofenadine | H1 antagonist

Loratadine | H1 antagonist

Amthamine | H2 agonist

Dimaprit | H2 agonist

ABT 239 | H3 antagonist

Ciproxifan | H3 antagonist

Clobenpropit | H3 antagonist

Iodophenpropit | H3 antagonist

PF 3654746 | H3 antagonist

Imetit | H3 agonist

Immepip | H3 agonist

Immethridine | H3 agonist

 

See more HR Ligands (click)