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XE 991 dihydrochloride

CAS 122955-42-4

C26H20N2O.2HCl  MW 449.37

Purity: >99%

Soluble in water and DMSO

Ordering Information:

Cat. No. Axon 1305

Qty1: 10 mg / €95  $124

Promotion: 2 x 10 mg  @  €140  $182

Qty2: 50 mg / €335  $436 

Promotion: 2 x 50 mg  @  €460  $598

Qty3: on request (* in stock of grams)

Send enquiry to: order@axonmedchem.com

or by fax to: +31-50-3600390.

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Biological Activity:   KCNQ channel and M-current blocker; potential AD therapeutic   References: online ref 1, 2, 3   Wanget al. KCNQ2 and KCNQ3 potassium channel subunits: molecular correlates of the M-channel. Science 1998, 282 1890.   Zaczek et al. Two new potent neurotransmitter release enhancers, 10,10-bis(4-pyridinylmethyl)-9(10H)-anthracenone and 10,10-bis(2-fluoro-4-pyridinylmethyl) -9(10H)-anthracenone: comparison to linopirdine. J. Pharmacol. Exp. Ther. 1998, 285 724.     Chemical Name: 10,10-bis(4-Pyridinylmethyl)-9(10H)-anthracenone dihydrochloride

XE 991 | KCNQ channel blocker | Axon Medchem | Axon 1305 | XE991

Axon Ligands TM - Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.