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SB 216763

 

CAS 280744-09-4

C19H12Cl2N2O2  MW 371.22

Purity: >99%

Soluble in DMSO

 

 

 

 

 

Ordering Information:

 

Cat. No. Axon 1303

 

Qty1: 10 mg / €95  $124 

Promotion: 2 x 10 mg @ €140 $182

Qty2: 50 mg / €335  $436

Promotion: 2 x 50 mg @ €500 $650

Qty3: on request

 

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Biological Activity:

 

Potent and selective glycogen synthase kinase-3 (GSK-3) inhibitor

 

 

References: online ref 1

 

L Facci et al. Glycogen synthase kinase-3 inhibitors protect central neurons against excitotoxicity. Neuroreport. 2003, 14(11), 1467-1470. [online]

 

Q Wang et al. Glycogen synthase kinase-3 is a negative regulator of extracellular signal-regulated kinase. Oncogene 2006, 25, 43–50. [online]

 

 

Chemical Name: 3-(2,4-Dichlorophenyl)-4-(1-methyl-1H-indol-3-yl)-1H-py rrole-2,5-dione

SB 216763 | GSK-3 inhibitor | Axon Medchem | Axon 1303 | SB216763

Axon Ligands TM - Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.

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Axon Ligands in this field:

(Wnt Signaling pathway)

 

BIO | GSK3 inhibitor

CHIR 98014 | GSK3 inhibitor

CHIR 99021 | GSK3 inhibitor

SB 216763 | GSK3 inhibitor

TWS 119 | GSK3β inhibitor

 

ICG 001 | Wnt/CREB inhibitor

XAV 939 | TNKS inhibitor

 

 

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