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Biological Activity:
Selective serotonin reuptake inhibitor (SSRI)
References: online 1
Wong et al., Prozac (fluoxetine, Lilly 110140), the first selective serotonin uptake inhibitor and an antidepressant drug: twenty years since its first publication. Life Sci.57, 411-441, (1995)
Gobert et al., Potentiation of the fluoxetine-induced increase in dialysate levels of serotonin (5-HT) in the frontal cortex of freely moving rats by combined blockade of 5-HT1A and 5-HT1B receptors with WAY 100,365 and GR 127,935. J. Neurochem.68, 1159-1163, (1997)
Chemical Name: Methyl-[3-phenyl-3-(4-trifluoromethyl-phenoxy)-propyl]-amine hydrochloride
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