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Zamifenacin fumarate

UK-76654

 

 

CAS 127308-98-9 (fumarate)

127308-82-1 (free base)

C31H33NO7  MW 531.6

Purity: 99%

 

 

 

 

Ordering Information:

 

Cat. No. Axon 1273

 

Qty1: 10 mg / €115  $150

 

Qty2: 50 mg / €415  $540 

 

Qty3: on request

 

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or by fax to: +31-50-3600390.

 

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Biological Activity:

 

Selective M3 muscarinic receptor antagonist

 

References: online ref 1

 

Houghton, L. A., et al. Zamifenacin (UK-76,654), a potent gut M3 selective muscarinic antagonist, reduces colonic motor activity in patients with irritable bowel syndrome. Aliment. Pharmacol. Ther, 1997, 11(3), 561-568.

 

 

Chemical Name: (R)-3-Benzhydryloxy-1-(2-benzo[1,3]dioxol-5-yl-ethyl)-piperidine fumarate

 

Zamifenacin (UK-76654) | M3 antagonist | Axon Medchem | Axon 1273

 

Axon LigandsTM - Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.

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Axon Ligands In The Field:

 

MDL 201012 | M3 antagonist

Zamifenacin | M3 antagonist

VU 0255035 | M1 antagonist

 

VU 0357017 | M1 PAM

VU 0152100 | M4 PAM

VU 0238429 | M5 PAM