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PD 166793

 

 

CAS 199850-67-4

C17H18BrNO4S 

MW 412.31

Purity: 99%

 

 

 

 

Ordering Information:

 

Cat. No. Axon 1271

 

Qty1: 10 mg / €90  $117

 

Qty2: 50 mg / €360  $468

 

Qty3: on request

 

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Biological Activity:

 

Matrix metalloproteinase (MMP) inhibitor

 

References: online 1, 2, 3

 

H León et al. Inhibition of matrix metalloproteinases prevents peroxynitrite-induced contractile dysfunction in the isolated cardiac myocyte. Br. J. Pharmacol. 2007, dec, advance online publication doi: 10.1038/sj.bjp.0707621

 

MM Sung et al. Matrix metalloproteinase-2 degrades the cytoskeletal protein α-actinin in peroxynitrite mediated myocardial injury. J. Mol. Cel. Cardiol. 2007, 43(4), 429-436. 

 

AL Chancey et al. Effects of Matrix Metalloproteinase Inhibition on Ventricular Remodeling Due to Volume Overload. Circulation 2002, 105, 1983-1988.

 

 

Chemical Name: (S)-2-(4'-Bromo-biphenyl-4-sulfonylamino)-3-methyl-butyric acid

 

PD 166793 | MMP inhibitor | Axon Medchem | Axon 1271 | PD166793

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Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.