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Biological Activity:
Potent and orally active antagonist of Gonadotropin releasing hormone (GnRH), also known as luteinising hormone releasing hormone (LHRH),
References: online 1, 2
Sarma et al. Peptidomimetic GnRH receptor antagonists for the treatment of reproductive and proliferative diseases. Expert Opinon on Ther. Patent. 2006, 16(6), 733-751.
Cho et al. Discovery of a novel, potent, and orally active nonpeptide antagonist of the human luteinizing hormone-releasing hormone (LHRH) receptor. J. Med. Chem. 1998, 41, 4190.
Chemical Name: 3-[(Benzyl-methyl-amino)-methyl]-7-(2,6-difluoro-benzyl)-2-(4-isobutyrylamino-phenyl)-4-oxo-4,7-dihydro-thieno[2,3-b]pyridine-5-carboxylic acid isopropyl ester
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