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T 98475

 

CAS 199119-18-1

192887-28-8 (HCl)

C37H37F2N3O4S  MW 657.77  

Purity: 98%

 

 

 

 

Ordering Information:

 

Cat. No. Axon 1270

 

Qty1: 2 mg (research sample) / inquire

 

Qty2: 5 mg (research sample) /inquire

 

Qty3: on request contract research synthesis

 

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Biological Activity:

 

Potent and orally active antagonist of Gonadotropin releasing hormone (GnRH), also known as luteinising hormone releasing hormone (LHRH),

 

References: online 1, 2

 

Sarma et al. Peptidomimetic GnRH receptor antagonists for the treatment of reproductive and proliferative diseases. Expert Opinon on Ther. Patent. 2006, 16(6), 733-751.

 

Cho et al. Discovery of a novel, potent, and orally active nonpeptide antagonist of the human luteinizing hormone-releasing hormone (LHRH) receptor. J. Med. Chem. 1998, 41, 4190.

 

 

Chemical Name: 3-[(Benzyl-methyl-amino)-methyl]-7-(2,6-difluoro-benzyl)-2-(4-isobutyrylamino-phenyl)-4-oxo-4,7-dihydro-thieno[2,3-b]pyridine-5-carboxylic acid isopropyl ester

 

T 98475 | GnRH (LHRH) antagonist | Axon Medchem | T98475 | Axon 1270

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Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.