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SSR 69071

 

 

CAS 344930-95-6

C27H32N4O7S  MW 556.63 

Purity: >98%

 

 

 

 

Ordering Information:

 

Cat. No. Axon 1269

 

Qty1: 10 mg / €145  $189

 

Qty2: 50 mg / inquire

 

Qty3: on request contract research synthesis

 

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or by fax to: +31-50-3600390.

 

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Biological Activity:

 

A highly potent human leukocyte elastase (HLE) inhibitor (0.02 nM)

 

References: online 1, 2

 

Z Kapui etal. Biochemical and pharmacological characterization of SSR69071, a novel orally active elastase inhibitor. J. Pharmacol. Exp. Ther. 2003, 102, 44263.

 

JP Bidouard et al. SSR69071, an elastase inhibitor, reduces myocardial infarct size following ischemia–reperfusion injury. Eur. J. Pharmacol. 2003, 461, 49-52.

 

 

Chemical Name:2-[[6-Methoxy-4-(1-methylethyl)-1,1-dioxido-3-oxo-1,2-b enzisothiazol-2(3H)-yl]methoxy]-9-[2-(1-piperidinyl)eth oxy]-4H-pyrido[1,2-a]pyrimidin-4-one   

 

SSR 69071 | Elastase inhibitor | Axon Medchem | SSR69071 | Axon 1269

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Axon LigandsTM

 

Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.