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DR 2313

 

 

CAS 284028-90-6

C8H10N2OS 

MW 182.24

Purity: >99%

 

 

 

 

Ordering Information:

 

Cat. No. Axon 1268     

 

Qty1: 10 mg /  €90  $117

 

Qty2: 50 mg / €360  $468

 

Qty3: on request

 

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Biological Activity:

 

Potent PARP inhibitor; with neuroprotective effects, potentially more useful in treating acute stroke than a free radical scavenger.

 

References: online 1

 

H Nakajima et al. A Newly Synthesized Poly(ADP-Ribose) Polymerase Inhibitor, DR2313 [2-Methyl-3,5,7,8-tetrahydrothiopyrano[4,3-d]-pyrimidine-4-one]: Pharmacological Profiles, Neuroprotective Effects, and Therapeutic Time Window in Cerebral Ischemia in Rats. JPET 2005, 312, 472-481.

 

 

 

 

Chemical Name: 2-Methyl-1,5,7,8-tetrahydro-thiopyrano[4,3-d]pyrimidin-4-one

 

DR 2313 | PARP inhibitor | Axon Medchem | Axon 1268 | DR2313

 

Axon LigandsTM - Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.

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Axon Ligands in the field:

 

ABT 888 | PARP inhibitor

AG 014699 | PARP inhibitor

DR 2313 | PARP inhibitor

Iniparib | PARP inhibitor

NU 1025 | PARP inhibitor

Olaparib | PARP inhibitor

 

 

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