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Biological Activity:
Potent PARP inhibitor; with neuroprotective effects, potentially more useful in treating acute stroke than a free radical scavenger.
References: online 1
H Nakajima et al. A Newly Synthesized Poly(ADP-Ribose) Polymerase Inhibitor, DR2313 [2-Methyl-3,5,7,8-tetrahydrothiopyrano[4,3-d]-pyrimidine-4-one]: Pharmacological Profiles, Neuroprotective Effects, and Therapeutic Time Window in Cerebral Ischemia in Rats. JPET 2005, 312, 472-481.
Chemical Name: 2-Methyl-1,5,7,8-tetrahydro-thiopyrano[4,3-d]pyrimidin-4-one
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