Gavestinel | Glycine antagonist | Axon Ligands | Axon Medchem

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Gavestinel - GV 150526A

CAS 153436-38-5

153436-22-7 (parent)

C18H11Cl2N2NaO3 MW 397.19

Purity: 99%

Ordering Information:

Cat. No. Axon 1262 Prime Source

Qty1: 10 mg / 115 $150

Qty2: 50 mg / 460 $598

Qty3: on request

Send enquiry to: order@axonmedchem.com

or by fax to: +31-50-3600390.

Biological Activity:

In vivo potent and selective antagonist of glycine site of NMDA receptor; orally bioavailable; neuroprotective in animal models of ischaemic stroke.

References: online 1

Mugnaini et al. Receptor binding characteristics of the novel NMDA receptor glycine site antagonist [³H]GV150526A in rat cerebral cortical membranes. Eur. J. Pharmacol. 2002, 391, 233.

Kajbaf et al. Pharmacokinetics, metabolism and excretion of the glycine antagonist GV150526A in rat and dog. Xenobiotica. 2003, 33, 415.

Chemical Name: 4,6-Dichloro-3-((E)-2-phenylcarbamoyl-vinyl)-1H-indole-2-carboxylic acid sodium salt

Gavestinel | Glycine antagonist | Axon Medchem | Axon 1262 | GV150526A

Axon Ligands ^TM - Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.