YM 298198 | mGLu1 Antagonist | Axon Ligands | Axon Medchem

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YM 298198 hydrochloride

CAS 748758-45-4

C18H23ClN4OS

MW 378.92

Purity: 99%

Ordering Information:

Cat. No. Axon 1260

Qty1: 10 mg / 105 $137

Qty2: 50 mg / 405 $527

Qty3: on request

Send enquiry to: order@axonmedchem.com

or by fax to: +31-50-3600390.

Biological Activity:

Selective mGLu1 antagonist

References: online ref 1

Fukunaga et al. Potent and specific action of the mGlu1 antagonists YM-298198 and JNJ16259685 on synaptic transmission in rat cerebellar slices. Br. J. Pharmacol. 2007, 151(6), 870-876.

Kohara et al. Radioligand binding properties and pharmacological characterization of 6-Amino-N-cyclohexyl-N,3-dimethyl-thiazolo[3,2-a]-benzimidazole-2-carboxamide (YM-298198), a high-affinity, selective and noncompetitive antagonist of metabotropic glutamate receptor type 1. J. Pharmacol. Exp. Ther. 2005, 315,163-169.

Chemical Name: 6-Amino-3-methyl-benzo[4,5]imidazo[2,1-b]thiazole-2-carboxylic acid cyclohexyl-methyl-amide hydrochloride

YM 298198 | mGLu1 Antagonist | Axon Medchem | Axon 1260 | YM298198

Axon Ligands ^TM- Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.