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Zebularine

 

 

CAS 3690-10-6

C9H12N2O5 

MW 228.07

Purity: >98%

 

 

 

 

Ordering Information:

 

Cat. No. Axon 1254

 

Qty1: 10 mg / €105  $137

 

Qty2: 50 mg / inquire

 

Qty3: on request

 

Send enquiry to: order@axonmedchem.com

or by fax to: +31-50-3600390.

 

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Biological Activity:

 

DNA methyltransferase (MTase) inhibitor, inhibiting DNA methylation; anticancer drug

 

References: online ref 1

 

L Zhou et al. Zebularine: a novel DNA methylation inhibitor that forms a covalent complex with DNA methyltransferases. J. Mol. Biol. 2002, 321(4), 591-599.

 

 

Chemical Name: 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-1H-pyrimidin-2-one

 

Zebularine | DNA methyltransferase inhibitor | Axon Medchem | Axon 1254

 

Axon Ligands TM - Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis. 

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Axon Ligands In The Field:

Enzymes - Transferases (click)

 

Decitabine | DNA MTase inhibitor

RG 108 | DNA MTase inhibitor

Zebularine | DNA MTase inhibitor

 

BIX 01294 | HMTase inhibitor

UNC 0224 | HMTase inhibitor

LB 42708 | FTase inhibitor

 

 

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