Chemistry Service Platform - CRO in Medicinal Chemistry

Axon Ligands (TM) - alphabetic: [A] [B] [C] [D] [E] [F] [G] [H] [I] [J] [K] [L] [M] [N] [O] [P] [Q] [R] [S] [T] [U] [V] [W] [X] [Y] [Z]

 

 

  

SCH 58261

 

 

 

CAS160098-96-4

C18H15N7O MW 345.36

Purity: 99 %

 

 

 

 

Ordering Information:

 

Cat. No. Axon 1253

 

Qty1: 5 mg / €90  $117

 

Qty2: 25 mg / €340  $442

 

Qty3: on request

 

Send enquiry to: order@axonmedchem.com

or by fax to: +31-50-3600390.

 

Contact us for payment and tech support.

Biological Activity:

 

Highly selective and potent A2A adenosine receptor antagonist

 

References: online 1, 2, 3

 

P Popoli MD et al. Effects of SCH 58261, an Adenosine A2A Receptor Antagonist, on Quinpirole-Induced Turning in 6-Hydroxydopamine-Lesioned Rats: Lack of Tolerance after Chronic Caffeine Intake. Neuropsychopharmacol. 2000, 22, 522-529.
 

C Zocchi et al. The non-xanthine heterocyclic compound SCH 58261 is a new potent and selective A2a adenosine receptor antagonist. J. Pharmacol. Exp. Ther. 1996, 276(2), 398-404.

 

 

Chemical Name: 2-(2-Furanyl)-7-(2-phenylethyl)-7H-pyrazolo[4,3-e][1,2, 4]triazolo[1,5-c]pyrimidin-5-amine  
 

SCH 58261 | A2A antagonist | Axon Medchem | Axon 1253 | SCH58261

 

Axon Ligands TM - Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.

axonmedchem.com © 2012

 

Axon Adenosine Receptor (AR) Ligands: e.g.

 

KW 6002 | A2A antagonist

SCH 442416 | A2A antagonist

SCH 58261 | A2A antagonist

 

CGS 21680 | A2A agonist

UK 432097 | A2A agonist

 

ADAC | A1 agonist

2-Chloroadenosine | A1/2A ago.

GR 79236 | A1 agonist

SDZ WAG 994 | A1 agonist

 

Rolofylline | A1 antagonist

Rolofylline M1-trans | A1 antag.

Rolofylline M1-cis | A1 antag.