Zatebradine | HCN Channel Blocker | Axon Ligands | Axon Medchem

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Zatebradine hydrochloride

UL-FS49

CAS 91940-87-3 (HCl)

85175-67-3 (free base)

C26H36N2O5.HCl MW 492.85

Purity: >98%

Ordering Information:

Cat. No. Axon 1248

Qty1: 10 mg / €115 $150

Qty2: 50 mg / €460 $598

Qty3: on request

Send enquiry to: order@axonmedchem.com

or by fax to: +31-50-3600390.

Biological Activity:

HCN channel blocker: blocker of neuronal I_h, related cardiac I_f channels and ATP-sensitive K_ir channels; specific bradycardic agent.

References:

PP Van Bogaert and F Pittoors. Use-dependent blockade of cardiac pacemaker current (If) by cilobradine and zatebradine. Eur. J. Pharmacol. 2003, 478, 161-171.

L Sen et al. Acute effects of zatebradine on cardiac conduction and repolarization. J. Cardiovasc. Pharmacol. 2002,7, 29-38.

Chemical Name: 3-(3-{[2-(3,4-Dimethoxy-phenyl)-ethyl]-methyl-amino}-propyl)-7,8-dimethoxy-1,3,4,5-tetrahydro-benzo[d]azepin-2-one hydrochloride

Zatebradine | HCN Channel Blocker | Axon Medchem | Axon 1248

Axon Ligands ^TM - Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.

Axon Ligands In The Field:

Zatebradine | HCN chan. Blocker

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