Chemistry Service Platform - CRO in Medicinal Chemistry

Axon Ligands (TM) - alphabetic: [A] [B] [C] [D] [E] [F] [G] [H] [I] [J] [K] [L] [M] [N] [O] [P] [Q] [R] [S] [T] [U] [V] [W] [X] [Y] [Z]

 

 

 

  

Eliprodil

SL 820715 

 

CAS 119431-25-3

C20H23ClFNO

MW 347.86

Purity: 99%

 

 

 

 

Ordering Information:

 

Cat. No. Axon 1246

 

Qty1: 10 mg / 95  $124

 

Qty2: 50 mg / 335  $436

 

Qty3: on request

 

Send enquiry to: order@axonmedchem.com

or by fax to: +31-50-3600390.

 

Contact us for payment and tech support.

Biological Activity:

 

Non-competitive NMDA antagonist, selective for NR2B type; Neuroprotective agent.

 

References: online 1

 

C Carter et al. Eliprodil: a novel neuroprotective agent acting at a modulatory site of the NMDA receptor. Neuropsychopharmacol. 1994, 11, 257-258.

 

Lengyel et al. Effect of a neuroprotective drug, eliprodil on cardiac repolarisation: importance of the decreased repolarisation reserve in the development of proarrhythmic risk. Br. J. Pharmacol. 2004, 143, 152.

 

 

Chemical Name: 1-(4-Chloro-phenyl)-2-[4-(4-fluoro-benzyl)-piperidin-1-yl]-ethanol

 

Eliprodil | NMDA antagonist | Axon Medchem | Axon 1246 | SL820715

 

Axon Ligands TM - Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.

axonmedchem.com © 2012

 

Axon Ligands in this field:

 

CP 101606 | NMDA antagonist

Ifenprodil | NMDA antagonist

Eliprodil | NMDA antagonist

N20C | NMDA antagonist

Gavestinel | Glycine antagonist

Ro 25-6981 | NMDA antagonist

Lamotrigine | Glutamate antago.

 

CFM-2 | AMPA antagonist

CNQX | AMPA/kanaite antagonist

DNQX | AMPA/kainate antagonist

GYKI 53655 | AMPA antagonist

YM-90K | AMPA antagonist

 

AZ 12216052 | mGluR8 PAM

BINA | mGluR2 PAM 

CPPHA | mGluR5 PAM

(S)-3,5-DHPG | mGluR1 agonist

VU-29 | mGuR5 PAM

LY 367385 | mGluR1a antagonist

YM 298198 | mGluR1 antagonist

Fenobam | mGluR5 antagonist

MPEP | mGluR5 antagonist