Chemistry Service Platform - CRO in Medicinal Chemistry

Axon Ligands (TM) - alphabetic: [A] [B] [C] [D] [E] [F] [G] [H] [I] [J] [K] [L] [M] [N] [O] [P] [Q] [R] [S] [T] [U] [V] [W] [X] [Y] [Z]

 

 

 

  

ALX 5407 hydrochloride - NFPS

 

 

CAS 200006-08-2 (HCl)

571147-18-7 (free base)

C24H24FNO3.HCl  MW 429.91

Purity: >98% (optically pure)

 

 

 

 

Ordering Information:

 

Cat. No. Axon 1238

 

Qty1: 10 mg / €145  $189

 

Qty2: 50 mg / inquire

 

Qty3: on request

 

Send enquiry to: order@axonmedchem.com

or by fax to: +31-50-3600390.

 

Contact us for our product range and services.

Biological Activity:

 

Potent, selective, irreversible hGlyT-1 glycine transporter inhibitor.

 

References: online ref 1

 

Atkinson BN et al. ALX 5407: a potent, selective inhibitor of the hGlyT1 glycine transporter. Mol Pharmacol. 2001, 60(6), 1414-20.

 

K Hashimoto. Glycine Transporter Inhibitors as Therapeutic Agents for Schizophrenia. Recent Patents on CNS Drug Discovery, 2006, 1, 43-53. [online]
 

 

Chemical Name: {[(R)-3-(Biphenyl-4-yloxy)-3-(4-fluoro-phenyl)-propyl]-methyl-amino}-acetic acid hydrochloride

 

ALX 5407 | hGlyT-1 inhibitor | Axon Medchem | Axon 1238 | ALX5407 - NFPS

axonmedchem.com © 2011

 

Axon Ligands in the field:

 

ALX 5407 | GlyT-1 inhibitor

Org 25935 | GlyT-1 inhibitor

SSR 504734 | GlyT-1 inhibitor

 

 

 

 

 

Axon Ligands TM    

Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.