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Biological Activity:
A regioisomer of cannabidiol without psychotropic activity; inactive at CB1 or CB2 receptors. However, it activates a third type of non-CB1/CB2 endo-cannabinoid receptor. Mechanism is under study.
References:
Z Járai et al. Cannabinoid-induced mesenteric vasodilation through an endothelial site distinct from CB1 or CB2 receptors. Proc. Natl. Acad. Sci. USA 1999, 96(24), 14136-14141.
L Walter et al. Nonpsychotropic cannabinoid receptors regulate microglial cell migration. J. Neurosci. 2003, 23(4), 1398-1405.
Chemical Name: 4-((1R,6R)-6-Isopropenyl-3-methyl-cyclohex-2-enyl)-5-pentyl-benzene-1,3-diol
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