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Cannabidiol

CBD

CAS 13956-29-1

C21H30O2 MW 314.46

Purity: 98%

(DEA controlled substance)

Ordering Information:

Cat. No. Axon 1234

Qty1: 10 mg / €105  $137

Qty2: 50 mg / €385  $501

Qty3: on request

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Biological Activity:   *** In the Spotlight of Recent Research ***   Cannabidiol does not bind to CB1 or CB2 receptors but it does block the effects of cannabinoid agonists by an unknown indirect way. Recently it was found to be an antagonist at the putative new cannabinoid receptor, GPR55, a GPCR expressed in the caudate nucleus and putamen; a promising therapeutic agent for the treatment of psychosis, hyperalgesia, seizures, and stroke.   References: online 1   A Thomas et al. Cannabidiol displays unexpectedly high potency as an antagonist of CB1 and CB2 receptor agonists in vitro. Br. J. Pharmacol. 2007, 150 (5), 613–23. doi:10.1038/sj.bjp.0707133. PMID 17245363.    E Ryberg et al. The orphan receptor GPR55 is a novel cannabinoid receptor. Br. J. Pharmacol. 2007, 152, 1092–1101. doi:10.1038/sj.bjp.0707460. PMID 17876302.    LE Long et al. The pharmacological actions of cannabidiol. Drugs Fut. 2005, 30(7), 747-753.     Chemical Name: 2-((1R,6R)-6-Isopropenyl-3-methyl-cyclohex-2-enyl)-5-pentyl-benzene-1,3-diol

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