Chemistry Service Platform - CRO in Medicinal Chemistry

Axon Ligands (TM) - alphabetic: [A] [B] [C] [D] [E] [F] [G] [H] [I] [J] [K] [L] [M] [N] [O] [P] [Q] [R] [S] [T] [U] [V] [W] [X] [Y] [Z]

 

 

  

WY 14643

 

 

CAS 50892-23-4

C14H14ClN3O2S

MW 323.80

Purity: >98 %

 

 

 

 

Ordering Information:

 

Cat. No. Axon 1227

 

Qty1: 10 mg / €45  $59

 

Qty2: 50 mg / €135  $176

 

Qty3: on request

 

Send enquiry to: order@axonmedchem.com

or by fax to: +31-50-3600390.

 

Contact us for payment and tech support.

Biological Activity:

 

Selective PPARα agonist

 

References:

 

Forman et al. Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors α and d. Proc. Natl. Acad. Sci. USA 1997, 94, 4312.

 

Bishop-Bailey. Peroxisome proliferator-activated receptors in the cardiovascular system. Br. J. Pharmacol. 2000, 129, 823.

 

 

Chemical Name: [4-Chloro-6-(2,3-dimethyl-phenylamino)-pyrimidin-2-ylsulfanyl]-acetic acid
 

WY 14643 | PPARα agonist | Axon Medchem | Axon 1227 | WY14643

axonmedchem.com © 2012

 

Axon Ligands in the field:

Nuclear Receptors - PPAR (click)

 

GW 7647 | PPAR α agonist

KRP 297 | PPAR α/γ agonist

WY 14643 | PPAR α agonist

 

GSK 3787 | PPAR δ antagonist