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U 73122

 

 

CAS 112648-68-7

C29H40N2O3  MW 464.65

Purity: >98 %

Soluble in DMSO to 11 mM

 

 

 

 

 

Ordering Information:

 

Cat. No. Axon 1225     Prime Source

 

Qty1: 10 mg / €95  $124

 

Qty2: 50 mg / €355  $462

 

Qty3: on request

 

Send enquiry to: order@axonmedchem.com

or by fax to: +31-50-3600390.

 

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Biological Activity:

 

Phospholipase C (PLC) inhibitor

 

References:

 

Smith et al. U-73122: a potent inhibitor of human polymorphonuclear neutrophil adhesion on biological surfaces and adhesion-related effector functions. J. Pharmacol. Exp. Ther. 1996, 278, 320.

 

 

 

 

Chemical Name: 1H-Pyrrole-2,5-dione, 1-[6-[[(17b)-3-methoxyestra-1,3,5(10)-trien-17-yl]amino]hexyl]-

 

U 73122 | Phospholipase C inhibitor | Axon Medchem | U73122 | Axon 1225

 

Axon Ligands TM - Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.

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Axon Ligands In The Field:

 

CDIBA | cPLA2 inhibitor

U 73122 | PLC inhibitor

 

 

Click Here To See Featured Cell Signaling and Oncology Ligands from Axon Collection

 

 

About Phospholipase

Phospholipases are enzymes that hydrolyze phospholipids into fatty acids and other lipophilic substances. There are four major classes: PLA (PLA1 and PLA2), PLB, PLC and PLD. Furthermore,

there are two type of PLA2: secreted PLA2 (sPLA2) and cytosolic PLA2 (cPLA2).