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Axon Ligands (TM) - alphabetic: [A] [B] [C] [D] [E] [F] [G] [H] [I] [J] [K] [L] [M] [N] [O] [P] [Q] [R] [S] [T] [U] [V] [W] [X] [Y] [Z]

 

 

  

(±)-LY 367385

 

 

CAS 198419-90-8

C10H11NO4  MW 208.2

Purity: >98%

Soluble in water and DMSO

 

 

 

 

Ordering Information:

 

Cat. No. Axon 1224

 

Qty1: 10 mg / €80  $104

 

Qty2: 50 mg / €240  $312

 

Qty3: on request

 

Send enquiry to: order@axonmedchem.com

or by fax to: +31-50-3600390.

 

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Biological Activity:

 

LY367385 [198419-91-9] is a selective mGlu1a antagonist

 

References:

 

V Bruno et al. Neuroprotective activity of the potent and selective mGlu1a metabotropic glutamate receptor antagonist, (+)-2-methyl-4-carboxy phenylglycine (LY367385): comparison with LY357366, a broader spectrum antagonist with equal affinity for mGlu1a and mGlu5 receptors. Neuropharmacology 1999, 38, 199. [online]  

 

 

 

Chemical Name: 4-(Amino-carboxy-methyl)-3-methyl-benzoic acid

 

(±) LY 367385 | mGlu1a antagonist | Axon Medchem | Axon 1224 | LY367385

 

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Axon Ligands in the field:

 

(S)-DHPG | mGluR1 agonist

LY 367385 | mGluR1a antagonist

YM 298198 | mGluR1 antagonist

MPEP | mGluR5 antagonist

Fenobam | mGluR5 antagonist

 

AZ 12216052 | mGluR8 PAM

BINA | mGluR2 PAM

CPPHA | mGluR5 PAM

VU-29 | mGuR5 PAM

 

CP 101606 | NMDA antagonist

Ifenprodil | NMDA antagonist

Eliprodil | NMDA antagonist

N20C | NMDA antagonist

Gavestinel | Glycine antagonist

Ro 25-6981 | NMDA antagonist

 

CNQX | AMPA/kanaite antagonist

DNQX | AMPA/kainate antagonist

GYKI 53655 | AMPA antagonist

YM-90K | AMPA antagonist