MPEP | mGluR5 antagonist | Axon Ligands | Axon Medchem

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MPEP hydrochloride

CAS 219911-35-0 (HCl)

96206-92-7 (free base)

C14H11N.HCl MW 229.71

Purity: 99%

Ordering Information:

Cat. No. Axon 1222

Qty1: 10 mg / 75 $98

Qty2: 50 mg / 225 $293

Qty3: on request

Send enquiry to: order@axonmedchem.com

or by fax to: +31-50-3600390.

Biological Activity:

Potent and selective antagonist for metabotropic glutamate receptor subtype 5 (mGluR5); Systemically active in vivo.

References: online 1, 2

P. Bäckström et al. mGluR5 Antagonist MPEP Reduces Ethanol-Seeking and Relapse Behavior. Neuropsychopharmacology 2004, 29, 921928.

PM Lea et al. Neuroprotective activity of the mGluR5 antagonists MPEP and MTEP against acute e. Br. J. Pharmacol. 2005, 145, 527-534.

Chemical Name: 2-Methyl-6-phenylethynyl-pyridine hydrochloride

MPEP | mGluR5 antagonist | Axon Medchem | Axon 1222

Axon Ligands ^TM - Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.