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ICI 192605  - ICI-192,605

CAS 117621-64-4

C22H23ClO5 MW 402.88

Purity: >98%

Soluble in DMSO and EtOH

Ordering Information:

Cat. No. Axon 1210      Prime Source

Qty1: 10 mg / €120  $156

Qty2: 50 mg / €460  $598

Qty3: on request

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Biological Activity:   A potent and selective, orally active thromboxane A2 (TP) receptor antagonist   References: online 1, 2, 3   Al-Jarad et al. Effects of a thromboxane receptor antagonist on prostaglandin D2 and histamine induced bronchoconstriction in man. Br. J. Clin. Pharmacol. 1994, 37, 97.   Shaw et al. Combined administration of 5-HT2 and thromboxane A2 antagonists: effects on platelet aggregation and isolated cardiac muscle. Br. J. Pharmacol. 1997, 121(5), 875–882.     Chemical Name: (Z)-6-[(2S,4S,5R)-2-(2-Chloro-phenyl)-4-(2-hydroxy-phenyl)-[1,3]dioxan-5-yl]-hex-4-enoic acid

ICI 192605 | Thromboxane A2 (TP) antagonist | Axon Medchem | Axon 1210 | ICI192605 - ICI-192,605

Axon Ligands TM - Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.

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Axon Ligands In The Field:

MK 0524 | DP1 antagonist

S 5751 | DP antagonist

ONO 8711 | EP1 antagonist

ICI 192605 | TP antagonist