Chemistry Service Platform - CRO in Medicinal Chemistry

 

 

 

  

Piribedil

 

 

CAS3605-01-4

C16H18N4O2 

MW 298.34

Purity: >98%

 

 

 

 

Ordering Information:

 

Cat. No. Axon 1198

 

Qty1: 10 mg / €75  $98

 

Qty2: 50 mg / €225  $293

 

Qty3: on request

 

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Biological Activity:

 

Direct dopamine agonist, with affinity for subtypes: D3 > D2 >> D1; an anti-parkinson drug marketed as Trivastal retard 50.

 

References: online

 

Cagnotto et al.  In vitro affinity of piribedil for dopamine D3 receptor subtypes, an autoradiographic study. Eur. J. Pharmacol. 1996, 313, 63.

 

 

 

 

 

 

 

 

Chemical Name: 2-(4-Benzo[1,3]dioxol-5-ylmethyl-piperazin-1-yl)-pyrimidine

 

Piribedil | Dopamine agonist | Axon Medchem | Axon 1198

 

Axon Ligands TM- alphabetic:  [A] [B] [C] [D] [E] [F] [G] [H] [I] [J] [K] [L] [M] [N] [O] [P] [Q] [R] [S] [T] [U] [V] [W] [X] [Y] [Z]

 

Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.

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Axon Dopamine Ligands: e.g.

 

S-(+)-Dinapsoline | D1 Agonist

GR 103691 | D3 antagonist

5-hydroxy-DPAT | D2 agonist

(S) 5-hydroxy-DPAT | D2 agonist

7-hydroxy-DPAT | D3 agonist

(R)-(+)-7-OH-DPAT | D3 agonist

Molindone | D2 antagonist

N-0426 | DA agonist

N 0734 | DA agonist  

NNC 776 | D1 antagonist

R(-)-NPA | D2 agonist

Rotigotine - N-0437 | DA agonist

(-)-Rotigotine | DA agonist

RU 24213 | D2 agonist

(±)-PD 128907 | D3 agonist

(+)-PD 128907 | D3 agonist

(+)-PHNO | D2 agonist

Piribedil | Dopamine agonist

PPHT - N-0434 | D2 agonist

SKF-83566 | D1 antagonist

ST 148 | D2 antagonist

ST 198 | D3 antagonist

TL 99 | Dopamine agonist

TL 102 | Dopamine agonist

TL 232 | Dopamine agonist

U 99194 | D3 antagonist