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Axon Ligands (TM) - alphabetic: [A] [B] [C] [D] [E] [F] [G] [H] [I] [J] [K] [L] [M] [N] [O] [P] [Q] [R] [S] [T] [U] [V] [W] [X] [Y] [Z]

 

 

 

  

SL 651498

 

 

CAS 205881-86-3

C23H20FN3O2  MW 389.43

Purity: 99 %

 

 

 

 

Ordering Information:

 

Cat. No. Axon 1195       Prime Source

 

Qty1:  5 mg (research sample) / €95  $124

Qty2: 10 mg (research sample) / €145  $189

Qty3: 50 mg (research sample) / €505  $657

 

Qty4: on request

 

Send enquiry to: order@axonmedchem.com

or by fax to: +31-50-3600390.

 

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Biological Activity:

 

GABAA agonist subtype a2 selective

 

 

References: online ref 1,2

 

G Griebel et al. SL651498: An Anxioselective Compound with Functional Selectivity for 2- and 3-Containing -Aminobutyric AcidA (GABAA) Receptors. J. Pharmaco. Eexp. Ther. 2001, 298(2), 753-768. [abstract]

 

NR Mirza et al. Comparative cue generalisation profiles of L-838,417, SL651498, zolpidem, CL218,872, ocinaplon, bretazenil, zopiclone and various benzodiazepines in chlordiazepoxide and zolpidem drug discrimination. J. Pharmacol. Exp. Ther. 2006, 316(3), 1291-1299. [abstract]

 

 

Chemical Name: 6-Fluoro-9-methyl-2-phenyl-4-(pyrrolidine-1-carbonyl)-2,9-dihydro-beta-carbolin-1-one

 

SL 651498 | GABAA agonist | Axon Medchem | Axon 1195 | SL651498 - SL-651,498

 

Axon Ligands TM - Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research and synthesis.

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Axon Ligands In The Field:

 

CP 615003 | GABAA agonist

L-838417 | GABAA agonist

Pagoclone | GABAA α2/3 agonist

SL 651498 | GABAA agonist

TP-003 | GABAA α3 agonist

NBI 34060 | GABAA PAM

NS 11394 | GABAA PAM

 

GS 39783 | GABAB PAM