Axon Ligands (TM) - alphabetic: [A] [B] [C] [D] [E] [F] [G] [H] [I] [J] [K] [L] [M] [N] [O] [P] [Q] [R] [S] [T] [U] [V] [W] [X] [Y] [Z]

BMS 189961

CAS262433-54-5

C23H26FNO4  MW 399.47

Purity: 99 %

Ordering Information:

Cat. No. Axon 1194

Qty1: 10 mg / €145  $189

Qty2: 50 mg / €505  $657

Qty3: on request

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Biological Activity:   Nuclear retinoic acid receptor (RAR) gamma agonist; its more active (R)-(+)-enantiomer is BMS 270394 (Axon 1173)   References: online ref 1   B P Klaholz et al. Enantiomer Discrimination Illustrated by High-Resolution Crystal Structures of the Human Nuclear Receptor hRARγ. Proc. Natl. Acad. Sci. USA. 2000, 97(12), 6322–6327.       Chemical Name: 3-Fluoro-4-[2-hydroxy-2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-acetylamino]-benzoic acid

BMS 189961 | RAR agonist | Axon Medchem | Axon 1194 | BMS189961

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Axon Ligands In The Field:

Nuclear Receptors - Retinoid Acid Receptor (RAR) (click)

BMS 189961 | RAR agonist

BMS 270394 | RAR agonist

CH 55 | RAR agonist

LE 135 | RAR antagonist