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TAK 637

(-)-TAK 637

CAS 183549-95-3
C30H25F6N3O2  MW 573.54
Purity: 98% (optically pure)

Ordering Information:

Cat. No. Axon 1186

Qty1: 1 mg (research sample) / inquire

Qty2: 5 mg (research sample) / inquire

Qty3: on request contract research synthesis

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Biological Activity:   Neurokinin-1 (NK1) antagonist, more active enantiomer in comparison with its opposite (R)-(+)-enantiomer (Axon 1187)   References:   S Okano et al., Effects of TAK-637, a Novel Neurokinin-1 Receptor Antagonist, on Colonic Function in Vivo. JPET 2001 298(2), 559-564. [online]   I Kamo and D Doe. Effect of TAK-637, a Tachykinin NK1-Receptor Antagonist, on Lower Urinary Tract Function in Cats. Jpn. J. Pharmacol. 2001, 86(2), 165-169. [online]     Chemical Name: (S)-7-(3,5-Bis-trifluoromethyl-benzyl)-9-methyl-5-p-tolyl-8,9,10,11-tetrahydro-7H-1,7,11a-triaza-cycloocta[b]naphthalene-6,12-dione

TAK 637 | NK1 antagonist | Axon Medchem | Axon 1186 | TAK637

Axon Ligands TM - Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.

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